A.S.N. Reddy...

Professor
Ph.D., Jawaharlal Nehru University
E-mail: Anireddy.Reddy@ColoState.EDU
Phone: 970-491-5773
Office: Anatomy/Zoology Building E321
Webpage: Click here for A.S.N. Reddy's Webpage

Description Of Research

Our group is interested in i) calcium-mediated signal transduction mechanisms with emphasis on calmodulin target proteins, ii) pre-messenger RNA splicing and iii) fungal resistance in plants. We use molecular, cell biological, genetic and biochemical approaches to accomplish our research goals. For additional details on our ongoing research projects please visit our website at http://lamar.colostate.edu/~reddy

Representative Publications

Liqun Du, Gul S. Ali, Kayla A. Simons, Jingguo Hou, Tianbao Yang, A.S.N. Reddy and B. W. Poovaiah (2009) Ca2+/calmodulin Regulates Salicylic Acid-mediated Plant Immunity. Nature 457: 1154-1158. Featured under “Leading Edge” section of Cell.

Maia V. Vinogradova, Galina G. Malanina, A. S.N. Reddy, Robert J. FlettericK (2009) Structure of the complex of a mitotic kinesin with its calcium binding regulator. Proc. Natl. Acad. Sci. 106, 8175-8179

Palusa, S. G. and Reddy, A.S.N. (2009) Extensive coupling of alternative splicing of pre-mRNAs of SR genes with nonsense-mediated decay. New Phytologist (in press).

Edited a Book on “Nuclear Pre-mRNA Processing in Plants” (Eds. A.S.N. Reddy and M. Golovkin) 2008 - published by Springer-Verlag.

Maia V. Vinogradova, Galina G. Malanina, V. S. Reddy, A.S.N. Reddy, R. J. Fletterick (2008) Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein. J Struc. Biol. 163:76-83 Featured on cover.

Ali, G.S., and Reddy, A.S.N (2008). PAMP-Triggered Immunity: Early events in the activation of flagellin sensitive2 . Plant Signaling &Behavior. 3:423-426

S. Schindler, K. Szafranski1, M. Hiller, G. S Ali, S. G. Palusa, Rolf Backofen, M. Platzer, A. S.N. Reddy (2008) Alternative splicing at NAGNAG acceptors in Arabidopsis thaliana SR and SR-related protein-coding gene. BMC Genomics 10: 9:159; pages 1-11.

Ali, G.S., Hanumappa, M., Prasad, K.V.S.K. and Reddy, A.S.N (2008). Analyses of in vivo interactions and mobility of two spliceosomal proteins using FRAP and BiFC. PLoS ONE 6;3(4):e1953; pages 1-13.

Reddy, A.S.N (2007) Alternative Splicing of pre-mRNAs in plants in the genomic era Ann. Rev. Plant Biology 58: 267-294.

Palusa, S.G., Ali, G.S. and Reddy, A.S.N. (2007) Alternative splicing of pre-mRNAs of Arabidopsis serine/arginine-rich proteins and its regulation by hormones and stresses. Plant J. 49: 1091-1107.

Day, I. and Reddy, A.S.N (2007) Proteomic Approaches to Construct Calcium Signaling Networks in Plants. In: Plant Proteomics: Technologies, Strategies, and Applications. Wiley Publisher; pages 645-657

Ali, G.S., Prasad, K.V.S.K., Day, I. and Reddy, A.S.N (2007). Ligand-dependent changes in the mobility of FLAGELLIN SENSITIVE2, an Arabidopsis receptor-like kinase. Plant Cell Physiol. 48: 1601-1611.

Ali, G.S., Palusa, S.G., Golovkin, M., Prasad, J., Manley, J. and Reddy, A.S.N (2007). A plant-specific splicing factor Regulates Multiple Developmental Processes PLoS ONE, 5: e471, Pages 1-13.

Ali, G. S. and Reddy, A.S. N. (2006) ATP, phosphorylation and transcription regulate the mobility of plant splicing factors. J. Cell Sci. 119: 3527-3538. (Featured on cover)

Richardson, D., Simmons, M., Reddy, A.S.N. (2006) Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes. BMC Genomics 7: 1-37. (designated as a highly accessed article)

Reddy, A.S.N. (2004) Plant serine/arginine-rich proteins and their role in pre-mRNA splicing. Trends in Plant Science 9: 541-547.

Vaka S. Reddy, Irene S. Day, Tyler Thomas and Reddy, A.S.N. (2004) KIC, a Novel Ca2+-Binding Protein with One EF-Hand Motif, Interacts with a Microtubule Motor Protein and Regulates Trichome Morphogenesis. Plant Cell 16: 185-200.

Vaka S. Reddy, and Reddy, A.S.N. (2004)Developmental and cell-specific expression of ZWICHEL is regulated by the intron and exon sequences of its upstream protein-coding gene. Plant Mol. Biol. 54: 273-293.

Ali, G.S., Golovkin, M., and Reddy, A.S.N. (2003). Nuclear localization and in vivo dynamics of a plant-specific serine/arginine-rich protein. Plant. J. 36: 883-893.

Golovkin, M. and Reddy, A.S.N (2003) A calmodulin-binding protein from Arabidopsis has an essential role in pollen germination. Proc. Natl. Acad. Sci. USA. 100: 10558-10663.

Irene S. Day Gul Shad Ali, Vaka S. Reddy and A.S.N. Reddy (2002) Analysis of EF-hand-containing proteins in Arabidopsis. Genome Biology 3: Research0056.1-0056.24.

Reddy, A.S.N. and Day, I (2001) Kinesins in the Arabidopsis genome: A comparative among analysis among eukaryotes. BMC Genomics 2:2.1-2.13.

Narasimhulu, S.B. and Reddy, A.S.N. (1998) Characterization of microtubule binding domains in the Arabidopsis kinesin-like calmodulin binding protein. Plant Cell 10: 957-965.

Bowser, J. and Reddy, A.S.N. (1997) Localization of a kinesin-like calmodulin-binding protein in dividing cells of Arabidopsis and tobacco. Plant J. 12: 1429-1438.

Golovkin, M. and Reddy, A.S.N. (1996) Structure and expression of a plant U1 snRNP 70K gene: Alternative splicing of U1 snRNP pre-mRNAs produces two different transcripts. Plant Cell 8: 1421-1435.

Reddy, A.S.N., Safadi, F., Narasimhulu, S.B., Golovkin, M. and Hu, X (1996) A novel plant calmodulin-binding protein with a kinesin heavy chain motor domain. J. Biol. Chem. 271: 7052-7060.