Description Of Research
Recombination nodules (RNs) are ellipsoidal particles lying on the central element of the synaptonemal complex (SC) during zygotene and pachytene of meiosis in eukaryotic organisms. RNs seem to reside at the sites of reciprocal recombination events in late pachytene nuclei. We are studying the temporal development, spatial distribution, and biochemistry of RNs and SCs. Our goal is to determine the roles of the SC and RNs in homologous chromosome synapsis, crossing over, and crossover interference.
Representative Publications
*Anderson, L.K., N. Salameh, H.W. Bass, L.C. Harper, W.Z. Cande, G. Weber, and S.M. Stack 2004. Integrating genetic linkage maps with pachytene chromosome structure in maize. Genetics 166:1923-1933
*Anderson, L.K., G.C. Doyle, B. Brigham, J. Carter, K.D. Hooker, A. Lai, M. Rice, and S.M. Stack 2003. High resolution Crossover maps for each bivalent of Zea mays using recombination nodules. Genetics 165:849-865.
Stack, S.M. and L.K. Anderson 2002. Crossing over as assessed by late recombination nodules is related to the pattern of synapsis and the distribution of early recombination nodules in maize. Chromosome Research 10:329-345.
Anderson, L.K., K.D. Hooker, and S.M. Stack 2001. The distribution of early recombination nodules on zygotene bivalents from plants. Genetics 159:1259-1269
Anderson, L.K. and S.M. Stack 2001. Distribution of early recombination nodules on zygotene bivalents from plants. Genetics 159:1259-1269
Stack, S.M. and L.K. Anderson. 2001. A model for chromosome structure during the mitotic and meiotic cell cycles. Chromosome Research 9:175-198
Peterson, D.G., N.L.V. Lapitan, and S.M. Stack. 1999. Localization of single- and low-copy sequences on tomato synaptonemal complex spreads using fluorescence hybridization (FISH). Genetics 152:427-439
Peterson, D.G., W.R. Pearson, S.M. Stack. 1998. Characterization of the tomato (Lycopsersicon esculentum) genome using in vitro and in situ DNA reassociation. Genome 41:346-356
