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SUMMARY:Consequences of rapid mtDNA evolution on nuclear gene variation, hy
 brid breakdown, and (possibly) speciation
LOCATION:Anatomy/Zoology Building W118
TZID:America/Denver
DTSTART:20140101T000000
UID:2026-05-13-06-41-30@natsci.colostate.edu
DTSTAMP:20260513T064130
Description:Abstract: Despite it small size\, the rapid evolution of the mi
 tochondrial genome (mtDNA) has significant implications for the evolution 
 of animal populations.  Mitochondrial function requires the transcription
  and translation of the mtDNA-encoded proteins that are essential for aero
 bic respiration\, and all these functions require proteins encoded in the 
 nuclear genome.  Consequently\, the many interactions between mtDNA and n
 ucDNA favor extensive intergenomic coadaptation.  When genetically diverg
 ent populations hybridize\, coadaptation can be disrupted and lead to mito
 chondrial dysfunction and reduced fitness (hybrid breakdown). Interpopulat
 ion crosses between populations of the copepod Tigriopus californicus show
  extensive hybrid breakdown due to intergenomic interactions affecting mit
 ochondrial function (manifested in reduced ATP production and increased ox
 idative damage).  Recent work using transcriptomic analyses of hybrid bre
 akdown and local adaptation in Tigriopus will also be discussed. 4:00 pm
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