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SUMMARY:Genomic Diversity and Relatedness in the Founding Black-footed Ferr
 et Population
LOCATION:Yates 206
TZID:America/Denver
DTSTART:20260611T110000
UID:2026-07-11-15-02-09@natsci.colostate.edu
DTSTAMP:20260711T150209
Description:Join Us for Robyn Bortner’s Master’s Defense Seminar!\n\nTh
 e Department of Biology at Colorado State University is excited to invite 
 you to a special Master’s defense seminar presented by graduate student 
 Robyn Bortner.\n\nThe black-footed ferret is one of North America’s most
  endangered mammals. In her defense\, Robyn will explore the genomic diver
 sity and relatedness of the founding population of this iconic species. He
 r research sheds light on the genetic challenges faced by conservation eff
 orts and provides insights into preserving biodiversity.\n\nEvent Details\
 nSpeaker: Robyn Bortner\nTitle: Genomic Diversity and Relatedness in the 
 Founding Black-footed Ferret Population\nDate: Thursday\, June 11\nTime: 1
 1:00 AM\nLocation: Yates 206\n\nCan\\'t make it in person? Join us on Team
 s!\ncol.st/v3770\n\nAdvised by Dr. Michael Antolin\, Emeritus Professor &a
 mp\; former Department Chair\, CSU Department of Biology\n\nWhether you\\'
 re passionate about wildlife conservation\, genetics\, or ecology\, this s
 eminar is a must-attend event for anyone interested in the natural science
 s. Don’t miss this opportunity to learn more about the intersection of g
 enomics and conservation biology. We hope to see you there!\nVisit our web
 site for more information on our seminars and follow us on social media f
 or more announcements from Biology.\n\n 	\nInstagram: @csubio\n 	\nTwitter
 /X: @csubiology\n 	\nFacebook: Department of Biology at Colorado State Uni
 versity\n\nAbstract\nBlack-footed ferrets (Mustela nigripes) are small obl
 igate carnivores native to North American prairie ecosystems. They have th
 e unfortunate but notable distinction of being assumed extinct twice in th
 eir history. Dependent on healthy prairie dog (Cynomys spp.) colonies for 
 both food and shelter\, black-footed ferrets most likely declined in respo
 nse to prairie habitat loss and fragmentation\, prairie dog eradication pr
 ograms\, and non-native disease\, most notably sylvatic plague (Yersinia p
 estis). After their rediscovery at a single site in Wyoming in 1981\, a su
 ccessful captive-breeding and reintroduction effort was formed with the la
 st 18 living individuals. Of these\, only 7 are considered to be genetic f
 ounders of the extant population. Coupled with the population’s isolated
  nature on the far western edge of the species range\, the founding black-
 footed ferrets had likely experienced a severe genetic bottleneck. Genetic
  management of the captive breeding population has been largely achieved t
 hrough pedigree analysis. Although studied prior to capture\, the relatedn
 ess of the founders is based on assumptions as they were all wild-caught\,
  and paternity in particular can be uncertain. The founders are also consi
 dered to be unrelated individuals\, but as they were all captured from the
  same dwindling source population\, their relationships to each other are 
 likely more complicated than studbook assumptions suggest. Fortunately\, s
 uitably preserved samples existed for 19 individuals of the source populat
 ion\, including the 7 assumed founders. For my research\, I used next gene
 ration sequencing data and bioinformatics focused on variant discovery to 
 characterize the amount of genomic variation in the founders\, estimate le
 vels of relatedness among the sampled individuals\, infer relationships\, 
 and compare to the current pedigree. Results confirmed some relationships 
 but contradicted others. Analysis also suggests that the founding populati
 on had a (not unexpected) higher level of background relatedness than is c
 urrently recorded. This work will inform further genetic investigation and
  conservation of the species.\n\n11:00 am
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