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SUMMARY:Extreme Physiology and the Mechanisms of Adaptation to High Altitud
 e
LOCATION:Bio 136
TZID:America/Denver
DTSTART:20230418T160000
UID:2026-03-09-09-23-52@natsci.colostate.edu
DTSTAMP:20260309T092352
Description:Aerobic performance is tied to fitness as it influences an anim
 al’s ability to find food\, escape predators\, or survive extreme condit
 ions. At high altitude\, where low oxygen availability and cold prevail\,
  maximum metabolic heat production (thermogenesis) is an aerobic performan
 ce trait that is intimately linked to survival. In this seminar\, I discus
 s the evolution of thermogenic performance in the North American deer mous
 e (Peromyscus maniculatus)\, a cosmopolitan rodent that can be found from 
 lowland prairies to the highest peaks in North America. I show that high-
 altitude deer mice have evolved enhanced thermogenic performance\, and the
 n detail what we know about the physiological and genetic mechanisms that 
 underlie this enhancement. I also show that the ontogeny of thermogenesis 
 is delayed at high altitude\, and detail why this delay may involve an ene
 rgetic trade-off. Overall\, our results highlight that natural selection s
 hapes aerobic performance at high-altitude across multiple\, intersecting 
 physiological systems. 4:00 pm
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