Stephen Stack

Stephen StackEmeritus Professor
Office: Anatomy/Zoology Building E343
Phone: 970-491-6802
Education: Ph.D., University of Texas, Austin
Email: Stephen.Stack@ColoState.EDU

Recombination nodules (RNs) are ellipsoidal particles lying on the central element of the synaptonemal complex (SC) during zygotene and pachytene of meiosis in eukaryotic organisms. RNs seem to reside at the sites of reciprocal recombination events in late pachytene nuclei. We are studying the temporal development, spatial distribution, and biochemistry of RNs and SCs. Our goal is to determine the roles of the SC and RNs in homologous chromosome synapsis, crossing over, and crossover interference.

Selected Publications

Anderson,L.K., P.A. Covey, L.R. Larsen, P. Bedinger, S.M. Stack. 2010. Structural differences in chromosomes distinguish species in the tomato clade. Cytogenetic and Genome Research 129:24-34.

Lindsay A. Shearer, Lorinda K. Anderson, Hans de Jong, Sandra Smit, José Luis Goicoechea, Bruce A. Roe, Axin Hua, James J. Giovannoni, and Stephen M. Stack. 2014. Fluorescence in situ hybridization and optical mapping To correct scaffold arrangement in the tomato genome.G3 4:1395-1405

The Tomato Genome Consortium. 2012. The tomato genome sequence provides insights into fleshy fruit evolution. Nature 485:635-641

*Anderson, L.K., N. Salameh, H.W. Bass, L.C. Harper, W.Z. Cande, G. Weber, and S.M. Stack 2004. Integrating genetic linkage maps with pachytene chromosome structure in maize. Genetics 166:1923-1933

*Anderson, L.K., G.C. Doyle, B. Brigham, J. Carter, K.D. Hooker, A. Lai, M. Rice, and S.M. Stack 2003. High resolution Crossover maps for each bivalent of Zea mays using recombination nodules. Genetics 165:849-865.

Stack, S.M. and L.K. Anderson 2002. Crossing over as assessed by late recombination nodules is related to the pattern of synapsis and the distribution of early recombination nodules in maize. Chromosome Research 10:329-345.

Anderson, L.K., K.D. Hooker, and S.M. Stack 2001. The distribution of early recombination nodules on zygotene bivalents from plants. Genetics 159:1259-1269

Anderson, L.K. and S.M. Stack 2001. Distribution of early recombination nodules on zygotene bivalents from plants. Genetics 159:1259-1269

Stack, S.M. and L.K. Anderson. 2001. A model for chromosome structure during the mitotic and meiotic cell cycles. Chromosome Research 9:175-198

Peterson, D.G., N.L.V. Lapitan, and S.M. Stack. 1999. Localization of single- and low-copy sequences on tomato synaptonemal complex spreads using fluorescence hybridization (FISH). Genetics 152:427-439

Peterson, D.G., W.R. Pearson, S.M. Stack. 1998. Characterization of the tomato (Lycopsersicon esculentum) genome using in vitro and in situ DNA reassociation. Genome 41:346-356